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Dr. Chavan's Fundraiser for Regulatory T Cell Research Lab at CHOC
Dr. Chavan's Fundraiser for Regulatory T Cell Research Lab at CHOC
The Hyundai Cancer Institute at CHOC Blood and Marrow Transplantation (BMT) Program also known as Stem cell transplant and cellular therapy program is made up of a team of highly trained oncology, hematology and cellular therapy experts, including dedicated nurse coordinators, social workers, nutritionists, physical therapist, pharmacists who assist patients and their families through the transplant process. Our cellular therapy program includes chimeric antigen receptor T (CAR-T) cells for ALL.
Most children who may benefit from a blood or bone marrow transplant are those with leukemia, including acute lymphoblastic leukemia (ALL) and acute myelogenous leukemia (AML). Other conditions that may respond to transplantation include hematologic disorders such as immune deficiencies and aplastic anemia, Hodgkin’s and non-Hodgkin’s lymphoma, Ewing’s sarcoma and solid tumors including some brain tumors and neuroblastoma.
The Hyundai Cancer Institute BMT Program is the only pediatric blood and bone marrow transplant program in Orange County and offers a full range of transplant procedures and services. Overall outcomes post hematopoietic stem cell transplant (HSCT) for children and young adults with acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML) continue to improve over the years. However, HSCT is often the last resort for high risk relapsed/refractory (r/r) leukemias and when these patients relapse post-HSCT the outcomes are dismal.
In addition to performing all the necessary clinical tests and procedures we also are actively engaged in research to help better the future outcomes for children with cancer. Our current pilot study aims to evaluate the clinical utility of sequential testing of regulatory T cells (Tregs), cytotoxic T cells (Tcons), natural killer (NK) cells, and relevant cytokines to predict potential relapse. While looking at treatment outcome factors, including presence and severity of graft vs versus host disease, as a secondary aims. Please help support BMT at CHOC by contributing to my fundraiser and sharing this page with your family and friends.
Every dollar raised will advance CHOC's great cause! Learn more about Determining the role of regulatory T cells in successful immunotherapy.at CHOC.
Most children who may benefit from a blood or bone marrow transplant are those with leukemia, including acute lymphoblastic leukemia (ALL) and acute myelogenous leukemia (AML). Other conditions that may respond to transplantation include hematologic disorders such as immune deficiencies and aplastic anemia, Hodgkin’s and non-Hodgkin’s lymphoma, Ewing’s sarcoma and solid tumors including some brain tumors and neuroblastoma.
The Hyundai Cancer Institute BMT Program is the only pediatric blood and bone marrow transplant program in Orange County and offers a full range of transplant procedures and services. Overall outcomes post hematopoietic stem cell transplant (HSCT) for children and young adults with acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML) continue to improve over the years. However, HSCT is often the last resort for high risk relapsed/refractory (r/r) leukemias and when these patients relapse post-HSCT the outcomes are dismal.
In addition to performing all the necessary clinical tests and procedures we also are actively engaged in research to help better the future outcomes for children with cancer. Our current pilot study aims to evaluate the clinical utility of sequential testing of regulatory T cells (Tregs), cytotoxic T cells (Tcons), natural killer (NK) cells, and relevant cytokines to predict potential relapse. While looking at treatment outcome factors, including presence and severity of graft vs versus host disease, as a secondary aims. Please help support BMT at CHOC by contributing to my fundraiser and sharing this page with your family and friends.
Every dollar raised will advance CHOC's great cause! Learn more about Determining the role of regulatory T cells in successful immunotherapy.at CHOC.
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